Calming the Autoantibody Attack in Hashimoto's Thyroiditis

Is it possible to calm the immune system and stop the onslaught of Hashimoto's thyroiditis?

Some people believe that it is possible to calm the immune system and stop Hashimotos' thyroiditis.

I'm not an expert on this and my reading on this area has been fairly patchy. However, for those that want to investigate this area more then I'll mention a few strategies that are talked about a great deal. These may be the starting point for those that want to find out more about reducing the TPO and Tg autoantibodies that are raised in Hashimoto's thyroiditis.

Strategies Believed to Calm the Immune System in Hashimoto's Thyroiditis

For a thyroid gland that is under attack by TPO and Tg autoantibodies then ensuring that the right thyroid treatment is in place and the patient is not hypothyroid in terms of FT3 and symptoms/signs is a good starting place.

The right thyroid hormone treatment will not be effective if cortisol levels are low. Consequently testing cortisol with a 24-hour adrenal saliva test and an 8:00am morning cortisol test and correcting low cortisol is essential. Many of my blog posts and parts of the 'Recovering with T3' book is concerned with the need for healthy adrenal output of cortisol and the use of the CT3M when necessary, so I will say no more about this subject here.

Vitamin D3 supplementation has been shown to be helpful in reducing the autoimmune attack in Hashimoto's thyroiditis. Vitamin D levels can be tested with a 25-hydroxy vitamin D test. Supplementation with vitamin D3 is essential if vitamin D is low. Supplementation with 5000 IUs of vitamin D3 may make sense even if vitamin D levels are within range. Some doctors recommend higher doses of vitamin D3 but it is important to take medical advice on vitamin D3 supplementation (especially if a patient has kidney issues as vitamin D can cause further kidney damage).

If iron levels are low this will put stress on the processing of thyroid hormones, so iron should be properly tested and supplemented if it is not at a healthy level.

Vitamin B12 and folate should also be tested as if these are low this will also create stress on the body and impair thyroid hormone action.

Selenium 200 mcg per day is also known to be effective in lowering autoantibodies.

Gluten is known to be a factor in the development of Hashimoto's thyroiditis. This is a massive topic in itself but one of the strategies that many thyroid patients adopt is to go gluten free. This and many other relevant topics may be found Datis Kharrazian's book 'Why do I still have symptoms when my lab tests are normal?'

Low dose naltexone (LDN) is a drug that is known to modulate the immune system. Many thyroid patients have had good results with LDN and have seen their TPO and Tg autoantibodies reduce significantly (these are the two main Hashimoto's autoantibodies):

Finally, Izabella Wentz has an excellent book entitled 'Hashimoto's Thyroiditis', and she appears to be one of the leading advocates for diet and supplementation to deal with Hashimoto's.

This blog post is just a menu of potential options that thyroid patients may wish to investigate further themselves.

However, I hop the above may provide some readers with a starting point for their own investigations.

Best wishes,


(Updated in February 2019)