I was recently asked a couple of questions related to whether T4 and T3 should be used in a fixed ratio and whether it is possible to pre-determine how much T3 someone might need. Here are the questions and my responses.
Q1: Could you please share your thoughts about ratios between T4 and T3. Natural desiccated thyroid has 4:1 the amount of T4 to T3 so shouldn't people take T4 and T3 together in this way?
There is a very simple argument that shows that maintaining a simplistic ratio of T4 to T3 of 4:1 is not going to work for all people.