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Research Studies: Use of Ranges is Flawed, rT3 is Active, TSH should NOT Guide Treatment

Can Adding Some T3 to Mostly T4 (NDT or Levothyroxine) Clear rT3 (Reverse T3)?

By Paul on Thu, 19/03/2015 - 13:07

I was recently asked by a friend whether it was true that by adding some T3 medication to their main thyroid medication of natural desiccated thyroid (NDT) or thyroxine (T4) that this would clear reverse T3 (rT3).

The answer to this is very simple. No, it won't clear rT3 if someone just adds some T3 to NDT or T4 medication - the basic science is very straightforward.

Let me explain.

Hungry for Sherbet Lemons?

By Paul on Sun, 23/09/2012 - 10:22

I've seen or heard many times viewpoints expressed that suggest that there are ideal levels of FT4 and FT3. I disagree with this.

Thyroid Blood Tests - What is Reverse T3?

By Paul on Thu, 02/02/2012 - 17:45

T4 is a relatively inactive hormone. T4 only becomes useful to the body after one of the D1 or D2 deiodinase enzymes converts it into the biologically active T3 hormone. Another deiodinase enzyme (D3), is able to convert some of the T4 into reverse T3 (often shortened to rT3). T3 cannot be converted into rT3.

The deiodinase enzymes can be upregulated or downregulated depending on the need to increase conversion from T4 to T3 or reduce it, and increase or decrease rT3.

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