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For those people who need to use T3 how many doses of T3 per day are best?

There is no one answer to this, as everyone needs just the right number of T3 doses of the right size to suit their needs.

Five doses of T3 per day are often not effective. This is because with five doses the T3 doses are often too low and are too close together. Many doses, taken frequently don't work very well because they often leave the tissues deficient in T3, which can raise heart rate or leave the person feeling hypothyroid.

Feb of 2011: Johannes Ott and colleagues from Kaiserin Elisabeth Spital and Medical University of Vienna, Austria, report that women with higher levels of anti-thyroid antibody had a significantly higher number of symptoms, even though their levels of thyroid-stimulating hormone (TSH)-a measure of thyroid function-did not differ from TSH levels measured in women with lower antibody levels....

Here is piece of research that helps to provide another reason why T3 helps some thyroid patients struggling with blood sugar issues:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041250/

Best wishes,

Paul

I have talked many times about the importance of glucose reaching the cells from the bloodstream. Our digestive system and insulin and cortisol all play a role in enabling blood sugar to flow into our cells.

Inside our cells the mitochondria use glucose to manufacture adenosine triphosphate (ATP), which is the chemical energy our cells use. Without enough ATP thyroid hormone will not be able to work. So, regardless of the thyroid hormone type, or the dosage of thyroid hormone, if ATP is low then the person will remain hypothyroid.