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Higher cortisol levels reduce TSH (through the effect on the hypothalamic-pituitary system), and this reduces T4 to T3 conversion. Lower cortisol levels increase TSH. resulting in an increase in T4 to T3 conversion. Studies have found that in severe cortisol deficiency, the TSH and FT3 are often high. Cortisol (HC) supplementation in these people, normalises the TSH and FT3.

Many guidelines strongly caution against the risk associated with low TSH. Some doctors and thyroid patients have jumped to the conclusion that a low TSH “causes” osteoporosis. Some even believe a low TSH must be avoided at all costs during thyroid therapy, even if lowering their thyroid hormone dose causes chronic hypothyroid symptoms in a patient!

But as of 2019, the truth is that real science still indicates that suppressed TSH is not responsible for any harm to bones.

I wrote a blog post recently entitled 'Physiological Replacement Therapy with T3 is Beneficial in Ischemic Heart Disease'. See: http://recoveringwitht3.com/blog/physiological-replacement-therapy-t3-beneficial-ischemic-heart-disease

Ischemic heart disease is caused by narrowed heart arteries and is also referred to as coronary artery disease or coronary heart disease.

Strangely, I was thinking today about who I am.

I hardly recognise myself at age 60 to the person I was when age 30.  Physically I am similar, recognisable but older. In my head I am so very different.